Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321405 | 1.00 | LMNA (0.59) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL13447781 | 0.91 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL15592369 | 0.91 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL17850294 | 0.91 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL17850343 | 0.91 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL13250764 | 0.91 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL14436577 | 0.88 | LMNA (0.46) | LMNAKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL5318022 | 0.88 | LMNA (0.48) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL14436052 | 0.88 | LMNA (0.48) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL5318024 | 0.88 | LMNA (0.48) | LMNAKMT2APOLBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093769-A1 | OLIGOSACCHARIDE BIOSYNTHESIS INHIBITORS | ISIS INNOVATION LIMITED (GB) | 2007-08-23 | — | — | WO | disclosed |