Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13271933 | 0.95 | LMNA (0.51) | LMNAKMT2APOLBMEN1USP2 | |
| SCHEMBL19786805 | 0.95 | LMNA (0.51) | LMNAKMT2APOLBMEN1USP2 | |
| SCHEMBL5321405 | 0.88 | LMNA (0.59) | LMNAKMT2APOLBMEN1USP2 | |
| SCHEMBL14437199 | 0.88 | LMNA (0.59) | LMNAKMT2APOLBMEN1USP2 | |
| SCHEMBL14436494 | 0.87 | POLB (0.43) | LMNAKMT2APOLBMEN1USP2 | |
| SCHEMBL5322879 | 0.87 | POLB (0.43) | LMNAKMT2APOLBMEN1USP2 | |
| SCHEMBL5320321 | 0.87 | POLB (0.43) | LMNAKMT2APOLBMEN1USP2 | |
| SCHEMBL5320327 | 0.87 | POLB (0.43) | LMNAKMT2APOLBMEN1USP2 | |
| SCHEMBL17850343 | 0.86 | LMNA (0.57) | LMNAKMT2APOLBMEN1USP2 | |
| SCHEMBL13447781 | 0.86 | LMNA (0.57) | LMNAKMT2APOLBMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093769-A1 | OLIGOSACCHARIDE BIOSYNTHESIS INHIBITORS | ISIS INNOVATION LIMITED (GB) | 2007-08-23 | — | — | WO | disclosed |