Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.36 |
| ▸ | STK10 | O94804 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505783 | 0.87 | CYP1A2 (0.34) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL14437279 | 0.83 | MEN1 (0.40) | MEN1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL14437200 | 0.82 | MEN1 (0.41) | MEN1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL14437272 | 0.81 | CISD1 (0.41) | MEN1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL14437276 | 0.81 | CISD1 (0.40) | MEN1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL14437286 | 0.79 | CISD1 (0.45) | MEN1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL5501669 | 0.79 | KMT2A (0.41) | MEN1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL14437294 | 0.78 | MEN1 (0.44) | MEN1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL5503552 | 0.77 | KMT2A (0.66) | MEN1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL5503915 | 0.77 | MEN1 (0.39) | MEN1KMT2AGAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253285-B2 | Thiazolinone 4-monosubstituted quinolines | HOFFMANN-LA ROCHE INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7253285-B2 | Thiazolinone 4-monosubstituted quinolines | HOFFMANN-LA ROCHE INC. (US) | 2007-08-07 | — | — | US | disclosed |