Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.63 |
| ▸ | DHODH | Q02127 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531759 | 0.85 | KDM4E (0.88) | KDM4EPLA2G2ADHODHMEN1KMT2A | |
| SCHEMBL8231320 | 0.84 | DHODH (0.70) | KDM4EPLA2G2ADHODHMEN1KMT2A | |
| SCHEMBL23590069 | 0.84 | KDM4E (0.86) | KDM4EPLA2G2ADHODHKMT2AALDH1A1 | |
| SCHEMBL29617657 | 0.84 | KDM4E (0.86) | KDM4EPLA2G2ADHODHKMT2AALDH1A1 | |
| SCHEMBL23590087 | 0.81 | KDM4E (0.69) | KDM4EPLA2G2ADHODHMEN1KMT2A | |
| SCHEMBL23590223 | 0.78 | KDM4E (0.68) | KDM4EPLA2G2ADHODHPOLBMEN1 | |
| SCHEMBL7823061 | 0.78 | KDM4E (0.79) | KDM4EPLA2G2ADHODHPOLBMEN1 | |
| SCHEMBL4017807 | 0.76 | CYP2D6 (0.65) | KDM4EPLA2G2ADHODHPOLBMEN1 | |
| SCHEMBL14825176 | 0.75 | KDM4E (0.73) | KDM4EPLA2G2ADHODHPOLBMEN1 | |
| SCHEMBL27491756 | 0.75 | KDM4E (0.71) | KDM4EPLA2G2ADHODHPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | KCNN3, KCNN2, HCN3 | KDM4E 2625/4885PLA2G2A 246/4885DHODH 3771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.