Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | TFPI | P10646 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543962 | 0.93 | KDM4E (0.37) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31002988 | 0.83 | FURIN (0.46) | F2CA12CA1CA9KDM4E | |
| SCHEMBL29544240 | 0.82 | NPY4R (0.42) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL14439367 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29855644 | 0.80 | NPY4R (0.38) | CA12CA1CA9KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29374860 | 0.79 | NPY4R (0.46) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1269496 | 0.78 | KDM4E (0.48) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL29567047 | 0.78 | KDM4E (0.48) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL30688763 | 0.78 | CA12 (0.45) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL19117207 | 0.78 | CA12 (0.60) | CA12CA1CA9KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |