Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 10/20 | 0.46 |
| ▸ | TFPI | P10646 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.41 |
| ▸ | NPY1R | P25929 | 6/20 | 0.41 |
| ▸ | NPY2R | P49146 | 4/20 | 0.41 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544240 | 0.95 | NPY4R (0.42) | NPY4RTFPINPY5RNPY1RNPY2R | |
| Trifluoroacetic Acid SCHEMBL29674974 | 0.94 | NPY4R (0.46) | NPY4RNPY5RNPY1RNPY2R | |
| Trifluoroacetic Acid SCHEMBL29375320 | 0.91 | NPY4R (0.49) | NPY4RNPY5RNPY1RNPY2RKDM4E | |
| SCHEMBL30688763 | 0.86 | CA12 (0.45) | NPY4RNPY5RNPY1RNPY2RKDM4E | |
| SCHEMBL11215355 | 0.85 | CA1 (0.49) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL31002988 | 0.85 | FURIN (0.46) | NPY4RNPY1RNPY2RKDM4EMEN1 | |
| SCHEMBL31045936 | 0.84 | SIRT5 (0.52) | NPY4RNPY1R | |
| SCHEMBL6858825 | 0.83 | NPY4R (0.46) | NPY4RNPY5RNPY1RNPY2RKDM4E | |
| SCHEMBL29961260 | 0.83 | RAB9A (0.46) | NPY4RNPY5RNPY1RNPY2RKDM4E | |
| SCHEMBL29543502 | 0.83 | CA12 (0.48) | KDM4EMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12350260-B2 | Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning | UNIVERSITE DE BRETAGNE OCCIDENTALE (FR) | 2025-07-08 | — | — | US | disclosed |
| US-20250197917-A1 | METHOD OF PROTEASE DETECTION | Sunbird Bio, Inc. | 2025-06-19 | — | — | US | disclosed |
| US-20250110130-A1 | EX VIVO PROTEASE ACTIVATION AND DETECTION | Sunbird Bio, Inc. | 2025-04-03 | — | — | US | disclosed |
| US-20220193048-A1 | PROTEASE-ACTIVATED RECEPTOR-2 INHIBITORS FOR THE TREATMENT OF SENSORY NEUROPATHY INDUCED BY A MARINE NEUROTOXIC POISONING | UNIVERSITE DE BRETAGNE OCCIDENTALE (FR) | 2022-06-23 | — | — | US | disclosed |
| EP-3946332-A1 | PROTEASE-ACTIVATED RECEPTOR-2 INHIBITORS FOR THE TREATMENT OF SENSORY NEUROPATHY INDUCED BY A MARINE NEUROTOXIC POISONING | Université de Bretagne Occidentale (FR) | 2022-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220193048-A1 | PROTEASE-ACTIVATED RECEPTOR-2 INHIBITORS FOR THE TREATMENT OF SENSORY NEUROPATHY INDUCED BY A MARINE NEUROTOXIC POISONING | PRSS12, TPSB2, F2RL1 | NPY4R 1525/4885TFPI 278/4885NPY5R 851/4885 |
| US-12350260-B2 | Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning | PRSS12, TPSB2, F2RL1 | NPY4R 1525/4885TFPI 278/4885NPY5R 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.