Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 8/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439383 | 0.86 | CTSS (0.43) | MEN1KMT2ACTSS | |
| SCHEMBL31002988 | 0.81 | FURIN (0.46) | KDM4EHPGDGAAALDH1A1MEN1 | |
| SCHEMBL1269496 | 0.81 | KDM4E (0.48) | KDM4EHPGDMAPTGAAALDH1A1 | |
| SCHEMBL29567047 | 0.81 | KDM4E (0.48) | KDM4EHPGDMAPTGAAALDH1A1 | |
| SCHEMBL14439368 | 0.80 | CRHR1 (0.37) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL29544240 | 0.80 | NPY4R (0.42) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL11457192 | 0.79 | KDM4E (0.46) | KDM4EHPGDMAPTGAAALDH1A1 | |
| SCHEMBL29565914 | 0.79 | KDM4E (0.46) | KDM4EHPGDMAPTGAAALDH1A1 | |
| SCHEMBL29565850 | 0.79 | KDM4E (0.46) | KDM4EHPGDMAPTGAAALDH1A1 | |
| SCHEMBL3362215 | 0.79 | KDM4E (0.46) | KDM4EHPGDMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |