Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CETP | P11597 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14444580 | 0.81 | TSHR (0.55) | TSHRCETPALDH1A1FOLH1SRC | |
| SCHEMBL13538603 | 0.80 | TSHR (0.50) | TSHRCETPALDH1A1FOLH1KDM4E | |
| SCHEMBL6135585 | 0.80 | TSHR (0.59) | TSHRCETPALDH1A1FOLH1SRC | |
| SCHEMBL4641409 | 0.80 | TSHR (0.64) | TSHRCETPALDH1A1FOLH1NPC1 | |
| SCHEMBL5327008 | 0.79 | TSHR (0.63) | TSHRCETPALDH1A1FOLH1NPC1 | |
| SCHEMBL9051512 | 0.79 | TSHR (0.53) | TSHRCETPALDH1A1FOLH1NPC1 | |
| SCHEMBL7290859 | 0.79 | TSHR (0.53) | TSHRCETPALDH1A1FOLH1NPC1 | |
| SCHEMBL30617844 | 0.79 | TSHR (0.53) | TSHRCETPALDH1A1FOLH1NPC1 | |
| SCHEMBL22402661 | 0.79 | TSHR (0.63) | TSHRCETPALDH1A1FOLH1SRC | |
| SCHEMBL4145460 | 0.79 | TSHR (0.53) | TSHRCETPALDH1A1FOLH1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |