Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206609 | 0.88 | TSHR (0.68) | TSHRELANECETPSRCIDO1 | |
| SCHEMBL5379773 | 0.82 | TSHR (0.61) | TSHRELANECETPSRCIDO1 | |
| SCHEMBL14439823 | 0.81 | TSHR (0.60) | TSHRCETPSRCPDPK1MTOR | |
| SCHEMBL20123381 | 0.80 | TSHR (0.59) | TSHRELANECETPSRCIDO1 | |
| SCHEMBL5327008 | 0.79 | TSHR (0.63) | TSHRCETPSRCIDO1PDPK1 | |
| SCHEMBL79996 | 0.79 | TSHR (0.63) | TSHRELANECETPSRCIDO1 | |
| SCHEMBL12239114 | 0.78 | TSHR (0.62) | TSHRELANECETPSRCPDPK1 | |
| SCHEMBL2301938 | 0.78 | TSHR (0.57) | TSHRELANECETPSRCIDO1 | |
| SCHEMBL218693 | 0.78 | TSHR (0.57) | TSHRELANECETPSRCIDO1 | |
| SCHEMBL2365443 | 0.78 | TSHR (0.57) | TSHRELANECETPSRCIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244718-B2 | Water soluble prodrugs of hindered alcohols | UNIVERSITY OF KANSAS (US) | 2007-07-17 | — | — | US | disclosed |