SCHEMBL6135585

SCHEMBL6135585

CCP(=O)(OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
CETP P11597 3/20 0.53
ALDH1A1 P00352 1/20 0.44
FOLH1 Q04609 1/20 0.43
SRC P12931 1/20 0.41
IDO1 P14902 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1238316 0.94 TSHR (0.56) TSHRCETPALDH1A1NPSR1
SCHEMBL30617844 0.90 TSHR (0.53) TSHRCETPALDH1A1FOLH1SRC
SCHEMBL28382525 0.87 TSHR (0.50) TSHRCETPSRCMEN1KMT2A
SCHEMBL5404588 0.84 CETP (0.58) TSHRCETPMEN1KMT2A
SCHEMBL5327008 0.83 TSHR (0.63) TSHRCETPALDH1A1FOLH1SRC
SCHEMBL13185883 0.82 TSHR (0.57) TSHRCETPALDH1A1FOLH1SRC
SCHEMBL6135587 0.82 TSHR (0.68) TSHRCETPALDH1A1FOLH1SRC
SCHEMBL4350991 0.81 TSHR (0.52) TSHRCETPNPSR1
SCHEMBL5850148 0.81 TSHR (0.61) TSHRCETPALDH1A1FOLH1SRC
SCHEMBL14439823 0.80 TSHR (0.60) TSHRCETPALDH1A1FOLH1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210394486-A1 ANTI-BLUSH AND CHEMICAL RESISTANT POLYESTER FILM TORAY PLASTICS AMERICA INC (US) 2021-12-23 US claimed
US-11110688-B2 Anti-blush and chemical resistant polyester film TORAY PLASTICS (AMERICA), INC. (US) 2021-09-07 US claimed
US-9931822-B2 Polyester film, use thereof and metal laminated sheet made of said film, and metal can and metal lid made of the sheet TOYO BOSEKI KABUSHIKI KAISHA (JP) 2018-04-03 US claimed
WO-2021155004-A1 STRAD-BINDING AGENTS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-08-05 WO disclosed
US-9931822-B2 Polyester film, use thereof and metal laminated sheet made of said film, and metal can and metal lid made of the sheet TOYO BOSEKI KABUSHIKI KAISHA (JP) 2018-04-03 US disclosed
US-9139604-B2 Antiviral phosphonate analogs GILEAD SCIENCES, INC. (US) 2015-09-22 US disclosed
US-20150025039-A1 ANTIVIRAL PHOSPHONATE ANALOGS GILEAD SCIENCES, INC. 2015-01-22 US disclosed
US-8871785-B2 Antiviral phosphonate analogs GILEAD SCIENCES, INC. (US) 2014-10-28 US disclosed
CN-103643522-A Production method for crease-resistant shirt JIANGSU GUIZU LAOYANDOU GARMENT CO LTD 2014-03-19 CN disclosed
CN-103643506-A Processing technology for ironing-free shirt JIANGSU GUIZU LAOYANDOU GARMENT CO LTD 2014-03-19 CN disclosed
US-20110319422-A1 PRODRUGS OF NH-ACIDIC COMPOUNDS: ESTER, CARBONATE, CARBAMATE AND PHOSPHONATE DERIVATIVES ALKERMES, INC. (US) 2011-12-29 US disclosed
US-7649015-B2 Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds GILEAD SCIENCES, INC. (US) 2010-01-19 US disclosed
EP-1186633-B1 Polyester film, use thereof and metal laminated sheet made of said film, and metal can and metal lid made of the sheet TOYO BOSEKI (JP) 2005-06-08 EP disclosed
US-20050053796-A1 Heat compression bonding; crystallization; impact strength TOYO BOSEKI KABUSHIKI KAISHA (JP) 2005-03-10 US disclosed
US-20020102419-A1 Polyester film, use thereof and metal laminated sheet made of said film, and metal can and metal lid made of the sheet TOYO BOSEKI KABUSHIKI KAISHA (JP) 2002-08-01 US disclosed
EP-1186633-A2 Polyester film, use thereof and metal laminated sheet made of said film, and metal can and metal lid made of the sheet Toyo Boseki Kabushiki Kaisha (JP) 2002-03-13 EP disclosed
WO-1999006062-A1 CYCLIC PEPTIDE ANTIFUNGAL AGENTS ELI LILLY AND COMPANY (US) 1999-02-11 WO disclosed
US-5780379-A Process for the stereospecific polymerization of alpha-olefins and catalyst system which can be employed for this polymerization SOLVAY POLYOLEFINS EUROPE-BELGIUM (SOCIETE ANONYME) (BE) 1998-07-14 US disclosed
WO-1996000733-A1 DIPHOSPHATE OR TRIPHOSPHATE NON-HYDROLYSABLE STABLE ANALOGUES AND METHODS FOR THEIR PREPARATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1996-01-11 WO disclosed
US-4558034-A Inhibitors of bacterial collagenase THE BOARD OF TRUSTEES OF THE UNIVERSITY OF KENTUCKY (US) 1985-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150025039-A1 ANTIVIRAL PHOSPHONATE ANALOGS TYMP, ITPA, PNP TSHR 4568/4885CETP 1281/4885ALDH1A1 4754/4885
US-20110319422-A1 PRODRUGS OF NH-ACIDIC COMPOUNDS: ESTER, CARBONATE, CARBAMATE AND PHOSPHONATE DERIVATIVES PHPT1, SI, CA6 TSHR 3662/4885CETP 1247/4885ALDH1A1 3126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.