Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2190601 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TDP1CYP3A4TSHRTP53 | |
| SCHEMBL3439540 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TDP1CYP3A4TSHRTP53 | |
| Hydrochloric Acid SCHEMBL10903841 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4TSHRTP53 | |
| SCHEMBL28001622 | 0.70 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRTP53 | |
| SCHEMBL1401588 | 0.70 | TSHR (0.48) | ALDH1A1TDP1CYP3A4TSHRTP53 | |
| SCHEMBL10046720 | 0.70 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRTP53 | |
| SCHEMBL487173 | 0.69 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4TSHRTP53 | |
| SCHEMBL27812431 | 0.69 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4TSHRTP53 | |
| SCHEMBL14449443 | 0.69 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRTP53 | |
| SCHEMBL21603434 | 0.69 | TP53 (0.44) | ALDH1A1TDP1CYP3A4TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |