Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.51 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.51 |
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.43 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.43 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429060 | 0.86 | P2RX3 (0.52) | P2RX3P2RX4P2RX2TYMPENPP1 | |
| SCHEMBL14440925 | 0.84 | TYMP (0.42) | TYMPLMNAALDH1A1TP53MAPT | |
| SCHEMBL14440209 | 0.83 | TYMP (0.50) | P2RX3P2RX2TYMPAHCYSLC29A1 | |
| SCHEMBL9002254 | 0.83 | P2RX3 (0.60) | P2RX3P2RX4P2RX2TYMPENPP1 | |
| SCHEMBL9141432 | 0.83 | P2RX3 (0.60) | P2RX3P2RX4P2RX2TYMPENPP1 | |
| SCHEMBL9002261 | 0.83 | P2RX3 (0.60) | P2RX3P2RX4P2RX2TYMPENPP1 | |
| SCHEMBL14428960 | 0.83 | P2RX3 (0.59) | P2RX3P2RX4P2RX2TYMPENPP1 | |
| SCHEMBL14440203 | 0.82 | TYMP (0.43) | TYMPLMNAALDH1A1TP53MAPT | |
| SCHEMBL972685 | 0.78 | LMNA (0.59) | P2RX3P2RX4P2RX2TYMPENPP1 | |
| SCHEMBL21877966 | 0.78 | LMNA (0.61) | P2RX3P2RX4P2RX2TYMPENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | P2RX3 1556/4885P2RX4 1633/4885P2RX2 2479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.