Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.62 |
| ▸ | AHCY | P23526 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.55 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.55 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.55 |
| ▸ | GAPDH | P04406 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | STAT6 | P42226 | 1/20 | 0.55 |
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.55 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14440224 | 1.00 | EHMT1 (0.62) | EHMT1AHCYRXFP1SMN1; SMN2ADORA3 | |
| SCHEMBL10590849 | 0.94 | EHMT1 (0.66) | EHMT1AHCYRXFP1SMN1; SMN2ADORA3 | |
| SCHEMBL8671033 | 0.89 | EHMT1 (0.74) | EHMT1AHCYRXFP1SMN1; SMN2ADORA3 | |
| SCHEMBL29936475 | 0.89 | EHMT1 (0.74) | EHMT1AHCYRXFP1SMN1; SMN2ADORA3 | |
| SCHEMBL8671037 | 0.89 | EHMT1 (0.74) | EHMT1AHCYRXFP1SMN1; SMN2ADORA3 | |
| SCHEMBL14440633 | 0.89 | EHMT1 (0.52) | EHMT1AHCYRXFP1SMN1; SMN2ADORA3 | |
| SCHEMBL14440209 | 0.89 | TYMP (0.50) | EHMT1AHCYRXFP1ADORA3ADORA2A | |
| SCHEMBL11489328 | 0.89 | EHMT1 (0.58) | EHMT1AHCYRXFP1SMN1; SMN2ADORA3 | |
| SCHEMBL9231760 | 0.87 | EHMT1 (0.76) | EHMT1AHCYRXFP1SMN1; SMN2ADORA3 | |
| SCHEMBL1637468 | 0.87 | EHMT1 (0.76) | EHMT1AHCYRXFP1SMN1; SMN2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
| WO-2007025043-A2 | SEVEN-MEMBERED RING NUCLEOSIDES | IDENIX PHARMACEUTICALS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | EHMT1 2870/4885AHCY 531/4885RXFP1 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.