Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.52 |
| ▸ | AHCY | P23526 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.45 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.45 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.45 |
| ▸ | GAPDH | P04406 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | STAT6 | P42226 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970121 | 0.94 | EHMT1 (0.56) | EHMT1AHCYNT5EGAARXFP1 | |
| SCHEMBL14440221 | 0.89 | EHMT1 (0.62) | EHMT1AHCYRXFP1ADORA1SMN1; SMN2 | |
| SCHEMBL14440224 | 0.89 | EHMT1 (0.62) | EHMT1AHCYRXFP1ADORA1SMN1; SMN2 | |
| SCHEMBL11489328 | 0.89 | EHMT1 (0.58) | EHMT1AHCYGAARXFP1ADORA1 | |
| SCHEMBL8970443 | 0.84 | EHMT1 (0.63) | EHMT1AHCYNT5ERXFP1ADORA1 | |
| SCHEMBL10590849 | 0.84 | EHMT1 (0.66) | EHMT1AHCYRXFP1ADORA1SMN1; SMN2 | |
| SCHEMBL8971323 | 0.83 | EHMT1 (0.59) | EHMT1AHCYGAAADORA1SMN1; SMN2 | |
| SCHEMBL8671033 | 0.82 | EHMT1 (0.74) | EHMT1AHCYRXFP1ADORA1SMN1; SMN2 | |
| SCHEMBL8671037 | 0.82 | EHMT1 (0.74) | EHMT1AHCYRXFP1ADORA1SMN1; SMN2 | |
| SCHEMBL29936475 | 0.82 | EHMT1 (0.74) | EHMT1AHCYRXFP1ADORA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | EHMT1 2870/4885AHCY 531/4885NT5E 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.