Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 6/20 | 0.44 |
| ▸ | PRKACA | P17612 | 8/20 | 0.42 |
| ▸ | PRKACG | P22612 | 8/20 | 0.42 |
| ▸ | PRKACB | P22694 | 8/20 | 0.42 |
| ▸ | CDK4 | P11802 | 4/20 | 0.42 |
| ▸ | CCND1 | P24385 | 4/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | PIM1 | P11309 | 4/20 | 0.42 |
| ▸ | PRKCB | P05771 | 8/20 | 0.41 |
| ▸ | PRKCA | P17252 | 7/20 | 0.41 |
| ▸ | PRKCH | P24723 | 7/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 7/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 7/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.41 |
| ▸ | PRKCG | P05129 | 3/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14440426 | 1.00 | CAMK2D (0.44) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL14440423 | 1.00 | CAMK2D (0.44) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL14440395 | 0.93 | PRKCB (0.42) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL14440401 | 0.93 | PRKCB (0.42) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL14440398 | 0.93 | PRKCB (0.42) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL14440403 | 0.93 | PRKCB (0.42) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL14440439 | 0.92 | CAMK2D (0.42) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL14440443 | 0.91 | CAMK2D (0.42) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL14440451 | 0.82 | KDR (0.41) | CAMK2DCDK4CCND1CCNE2CCNE1 | |
| SCHEMBL8353338 | 0.79 | PRKACA (0.43) | CAMK2DPRKACAPRKACGPRKACBCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262215-B2 | N-carbacycle monosubstituted indolocarbazoles as protein kinase inhibitors | NAD AG (DE) | 2007-08-28 | — | — | US | disclosed |