Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 10/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14440634 | 0.89 | ADK (0.39) | ADKPRMT5 | |
| SCHEMBL15948868 | 0.87 | ADK (0.40) | ADKPRMT5 | |
| SCHEMBL14440246 | 0.86 | ADK (0.40) | ADKPRMT5WDR77 | |
| SCHEMBL14440632 | 0.86 | ADK (0.40) | ADKPRMT5 | |
| SCHEMBL14440209 | 0.84 | TYMP (0.50) | — | |
| SCHEMBL14440598 | 0.81 | PRMT5 (0.36) | ADKPRMT5WDR77 | |
| SCHEMBL14440221 | 0.77 | EHMT1 (0.62) | — | |
| SCHEMBL14440224 | 0.77 | EHMT1 (0.62) | — | |
| SCHEMBL14440637 | 0.75 | PDE2A (0.37) | ADKPRMT5 | |
| SCHEMBL14440925 | 0.74 | TYMP (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | ADK 359/4885PRMT5 1055/4885WDR77 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.