SCHEMBL14440645

SCHEMBL14440645

Nc1ncnc2c1ccn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)C[C@H]1O

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 3/20 0.64
▸ METTL3 Q86U44 1/20 0.56
▸ PRMT5 O14744 3/20 0.52
▸ WDR77 Q9BQA1 1/20 0.52
▸ DNMT1 P26358 1/20 0.50
▸ DNMT3B Q9UBC3 1/20 0.50
▸ DPP4 P27487 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14568614 0.90 ADK (0.60) ADKMETTL3PRMT5WDR77DNMT1
Tubercidin SCHEMBL8259 0.87 ADK (0.82) ADKDNMT1DNMT3BDPP4
Tubercidin SCHEMBL11239877 0.87 ADK (0.82) ADKDNMT1DNMT3BDPP4
Tubercidin SCHEMBL6063615 0.87 ADK (0.82) ADKDNMT1DNMT3BDPP4
Tubercidin SCHEMBL23982350 0.87 ADK (0.82) ADKDNMT1DNMT3BDPP4
Tubercidin SCHEMBL23982115 0.87 ADK (0.82) ADKDNMT1DNMT3BDPP4
Tubercidin SCHEMBL1652797 0.87 ADK (0.82) ADKDNMT1DNMT3BDPP4
Tubercidin SCHEMBL23351430 0.87 ADK (0.82) ADKDNMT1DNMT3BDPP4
Tubercidin SCHEMBL20938187 0.87 ADK (0.82) ADKDNMT1DNMT3BDPP4
Tubercidin SCHEMBL20419149 0.87 ADK (0.82) ADKDNMT1DNMT3BDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070185063-A1 Seven-membered ring nucleosides IDENIX PHARMACEUTICALS, INC. 2007-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070185063-A1 Seven-membered ring nucleosides NSUN2, NSUN3, HAVCR2 ADK 359/4885METTL3 80/4885PRMT5 1055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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