Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.60 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.58 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14440645 | 0.90 | ADK (0.64) | ADKMETTL3PRMT5WDR77DNMT1 | |
| SCHEMBL14568724 | 0.88 | SLC29A1 (0.49) | ADKMETTL3SLC29A1 | |
| SCHEMBL14568617 | 0.88 | SLC29A1 (0.49) | ADKMETTL3SLC29A1 | |
| SCHEMBL15948766 | 0.86 | METTL3 (0.71) | ADKMETTL3PRMT5SLC29A1 | |
| SCHEMBL10079498 | 0.86 | METTL3 (0.71) | ADKMETTL3PRMT5SLC29A1 | |
| SCHEMBL25413618 | 0.86 | METTL3 (0.71) | ADKMETTL3PRMT5SLC29A1 | |
| SCHEMBL10060032 | 0.86 | METTL3 (0.71) | ADKMETTL3PRMT5SLC29A1 | |
| SCHEMBL30597658 | 0.86 | METTL3 (0.71) | ADKMETTL3PRMT5SLC29A1 | |
| Tubercidin SCHEMBL23351430 | 0.84 | ADK (0.82) | ADKSLC29A1DNMT1DNMT3B | |
| Tubercidin SCHEMBL1652797 | 0.84 | ADK (0.82) | ADKSLC29A1DNMT1DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025043-A2 | SEVEN-MEMBERED RING NUCLEOSIDES | IDENIX PHARMACEUTICALS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |