Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | CDC25B | P30305 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25C | P30307 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786986 | 0.92 | CDC25B (0.61) | HRH3CDC25BALDH1A1KDM4EHPGD | |
| SCHEMBL2119496 | 0.87 | TSHR (0.72) | HRH3CDC25BALDH1A1KDM4EHPGD | |
| SCHEMBL2117339 | 0.85 | ALDH1A1 (0.71) | HRH3CDC25BALDH1A1KDM4ETSHR | |
| SCHEMBL5030862 | 0.85 | HRH3 (0.53) | HRH3CDC25BALDH1A1KDM4EHPGD | |
| SCHEMBL7137986 | 0.85 | HRH3 (0.66) | HRH3CDC25BALDH1A1KDM4ETSHR | |
| SCHEMBL27540941 | 0.85 | HRH3 (0.66) | HRH3CDC25BALDH1A1KDM4EHPGD | |
| SCHEMBL14000083 | 0.84 | ADRB2 (0.56) | HRH3CDC25BALDH1A1KDM4EHPGD | |
| SCHEMBL15852963 | 0.84 | TSHR (0.71) | ALDH1A1KDM4EHPGDTSHRPOLB | |
| SCHEMBL1737390 | 0.83 | HRH3 (0.57) | HRH3CDC25BALDH1A1KDM4EHPGD | |
| SCHEMBL29534446 | 0.83 | HRH3 (0.57) | HRH3CDC25BALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9149440-B2 | Nanoparticles for drug-delivery | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-10-06 | — | — | US | disclosed |
| US-20070190160-A1 | Nanoparticles for drug-delivery | UNIVERSITY OF SOUTH FLORIDA | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190160-A1 | Nanoparticles for drug-delivery | EPCAM, TUBB1, ACTB | HRH3 3880/4885CDC25B 1232/4885ALDH1A1 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.