SCHEMBL14440933

SCHEMBL14440933

CCOC(=O)C1=Cc2c(ccc(C)c2F)OC1C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 20/20 0.48
PTGS1 P23219 17/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5645198 0.88 PTGS2 (0.58) PTGS2PTGS1
SCHEMBL5645650 0.84 PTGS2 (0.47) PTGS2PTGS1
SCHEMBL5647775 0.83 PTGS2 (0.46) PTGS2PTGS1
SCHEMBL5648714 0.82 PTGS2 (0.72) PTGS2PTGS1
SCHEMBL5646929 0.82 PTGS2 (0.51) PTGS2PTGS1
SCHEMBL5645328 0.81 PTGS2 (0.47) PTGS2PTGS1
SCHEMBL5642586 0.81 PTGS2 (0.57) PTGS2PTGS1
SCHEMBL5645484 0.81 PTGS2 (0.69) PTGS2PTGS1
SCHEMBL27900992 0.80 PTGS2 (0.45) PTGS2PTGS1
SCHEMBL27918786 0.80 PTGS2 (0.45) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7259266-B2 Benzopyran compounds useful for treating inflammatory conditions PHARMACIA CORPORATION (US) 2007-08-21 US disclosed