Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 16/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5647775 | 0.89 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL27900992 | 0.88 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL27918786 | 0.88 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL14440933 | 0.84 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL5646653 | 0.84 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL5644434 | 0.83 | PTGS2 (0.51) | PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL5647300 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL5644970 | 0.83 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL5668215 | 0.82 | PTGS2 (0.41) | PTGS2PTGS1MEN1MAPTKMT2A | |
| SCHEMBL5645328 | 0.82 | PTGS2 (0.47) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210186923-A1 | THERAPEUTIC FORMULATIONS AND USES THEREOF | PIEDMONT ANIMAL HEALTH LLC | 2021-06-24 | — | — | US | disclosed |
| US-7259266-B2 | Benzopyran compounds useful for treating inflammatory conditions | PHARMACIA CORPORATION (US) | 2007-08-21 | — | — | US | disclosed |
| EP-1631562-A1 | CHROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | Pharmacia Corporation (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1615905-A2 | BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS | Pharmacia Corporation (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20050148627-A1 | Benzopyran compounds for use in the treatment and prevention of inflammation related conditions | CARTER JEFFERY (US) | 2005-07-07 | — | — | US | disclosed |
| US-20050148777-A1 | Benzopyran compounds useful for treating inflammatory conditions | CARTER JEFFERY (US) | 2005-07-07 | — | — | US | disclosed |
| WO-2004087687-A1 | CHROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | PHARMACIA CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004087686-A2 | BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS | PHARMACIA CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148777-A1 | Benzopyran compounds useful for treating inflammatory conditions | PTGES2, PTGER2, PTGS2 | PTGS2 3/4885PTGS1 6/4885MEN1 4157/4885 |
| US-20210186923-A1 | THERAPEUTIC FORMULATIONS AND USES THEREOF | PTGES2, PTGES, PTGS2 | PTGS2 3/4885PTGS1 10/4885MEN1 4852/4885 |
| US-20050148627-A1 | Benzopyran compounds for use in the treatment and prevention of inflammation related conditions | PTGES2, PTGER2, PTGES | PTGS2 4/4885PTGS1 7/4885MEN1 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.