SCHEMBL14440974

SCHEMBL14440974

CCCCOC[C@@H]1C[C@H](OCCCC)C[C@@H](O)[C@H](n2cnc3c(N)ncnc32)O1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AHCY P23526 2/20 0.53
EHMT1 Q9H9B1 1/20 0.51
BCHE P06276 1/20 0.48
RXFP1 Q9HBX9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11036627 0.90 EHMT1 (0.57) AHCYEHMT1BCHERXFP1
SCHEMBL18950648 0.83 BCHE (0.56) AHCYEHMT1BCHE
SCHEMBL14440981 0.82 AHCY (0.49) AHCYEHMT1RXFP1
SCHEMBL9851825 0.79 EHMT1 (0.44) AHCYEHMT1BCHERXFP1
SCHEMBL9851835 0.79 EHMT1 (0.44) AHCYEHMT1BCHERXFP1
SCHEMBL23619452 0.79 BCHE (0.58) AHCYBCHE
SCHEMBL11416201 0.79 BCHE (0.58) AHCYBCHE
SCHEMBL15395472 0.78 AHCY (0.58) AHCYEHMT1BCHE
SCHEMBL15948883 0.78 ADORA2A (0.56) AHCYEHMT1
SCHEMBL20419166 0.78 AHCY (0.58) AHCYEHMT1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070185063-A1 Seven-membered ring nucleosides IDENIX PHARMACEUTICALS, INC. 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070185063-A1 Seven-membered ring nucleosides NSUN2, NSUN3, HAVCR2 AHCY 531/4885EHMT1 2870/4885BCHE 3255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.