Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.56 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.55 |
| ▸ | PI4KA | P42356 | 3/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | AHCY | P23526 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10220090 | 0.83 | ADORA2A (0.55) | ADORA2AADCY5PI4KAPI4K2BPI4K2A | |
| SCHEMBL10421736 | 0.83 | ADCY5 (0.63) | ADORA2AADCY5PI4KAPI4K2BPI4K2A | |
| SCHEMBL9471329 | 0.82 | ADCY5 (0.54) | ADORA2AADCY5PI4KAPI4K2BPI4K2A | |
| SCHEMBL15948858 | 0.79 | ADCY5 (0.56) | ADORA2AADCY5PI4KAPI4K2BPI4K2A | |
| SCHEMBL14440974 | 0.78 | AHCY (0.53) | AHCYEHMT1 | |
| SCHEMBL16769993 | 0.78 | ADK (0.47) | — | |
| SCHEMBL10421735 | 0.78 | ADCY5 (0.60) | ADORA2AADCY5PI4KAPI4K2BPI4K2A | |
| SCHEMBL15948724 | 0.78 | ADCY5 (0.60) | ADORA2AADCY5PI4KAPI4K2BPI4K2A | |
| SCHEMBL15942373 | 0.78 | ADCY5 (0.57) | ADORA2AADCY5PI4KAPI4K2BPI4K2A | |
| SCHEMBL15942372 | 0.78 | ADCY5 (0.57) | ADORA2AADCY5PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |