Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.71 |
| ▸ | XDH | P47989 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | NSD2 | O96028 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MPI | P34949 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030790 | 1.00 | KMT2A (0.71) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL12453311 | 0.88 | KMT2A (0.65) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL15457449 | 0.87 | L3MBTL1 (0.74) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL12522650 | 0.85 | MAPT (0.74) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL12826251 | 0.85 | KDM4E (0.54) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL15279257 | 0.84 | KDM4E (0.73) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL18211206 | 0.83 | NPC1 (0.69) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL22055809 | 0.82 | NPC1 (0.68) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL18211205 | 0.82 | NPC1 (0.68) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL12453329 | 0.81 | DUSP3 (0.76) | KMT2AMEN1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241783-B2 | Thrombopoietin mimetics | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |