Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445158 | 0.83 | CYP2C19 (0.45) | CYP2C19KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL13947123 | 0.83 | CYP2C19 (0.45) | CYP2C19KMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL31478057 | 0.82 | CPN1 (0.53) | CPN1CPB2ADRB2ADRB1ADRB3 | |
| SCHEMBL9114061 | 0.82 | CYP2C19 (0.67) | CYP2C19KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL14445141 | 0.79 | ALDH1A1 (0.46) | CYP2C19KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL7244093 | 0.78 | ALDH1A1 (0.43) | CYP2C19KMT2AMEN1L3MBTL1PTGS1 | |
| SCHEMBL6281451 | 0.77 | ESR1 (0.50) | CYP2C19L3MBTL1ESR1ESR2 | |
| SCHEMBL5879125 | 0.76 | SLC6A3 (0.49) | L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5879124 | 0.76 | SLC6A3 (0.49) | L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL624561 | 0.76 | SLC6A3 (0.49) | L3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247725-B2 | Gamma-aminoamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-7247725-B2 | Gamma-aminoamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-07-24 | — | — | US | disclosed |