Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445292 | 0.79 | ESR1 (0.31) | ESR1ESR2KLK1KDM4E | |
| SCHEMBL27530318 | 0.73 | KDM4E (0.35) | KLK1KDM4E | |
| SCHEMBL14445257 | 0.72 | CHRNB2 (0.41) | ESR1ESR2KDM4E | |
| SCHEMBL907933 | 0.68 | KDM4E (0.40) | KDM4E | |
| SCHEMBL11983585 | 0.68 | KDM4E (0.36) | KDM4E | |
| SCHEMBL24327716 | 0.68 | KDM4E (0.40) | KDM4E | |
| SCHEMBL24327721 | 0.68 | KDM4E (0.40) | KDM4E | |
| Hydrochloric Acid SCHEMBL6243425 | 0.67 | KDM4E (0.39) | KDM4E | |
| SCHEMBL21877286 | 0.65 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL11588513 | 0.65 | RAB9A (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247725-B2 | Gamma-aminoamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-7247725-B2 | Gamma-aminoamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-07-24 | — | — | US | disclosed |