SCHEMBL14445486

SCHEMBL14445486

Cc1c2c(cc3ccccc13)C(=O)c1ccccc1C2=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.45
CES1 P23141 1/20 0.45
DNMT1 P26358 2/20 0.44
ELANE P08246 2/20 0.44
ATM Q13315 1/20 0.44
BCL2 P10415 2/20 0.43
MCL1 Q07820 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CDC25B P30305 1/20 0.43
RAB9A P51151 3/20 0.42
ALDH1A1 P00352 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
PGAM1 P18669 2/20 0.42
PTK2B Q14289 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
NPC1 O15118 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CYP3A4 P08684 2/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17207363 0.87 CES1 (0.44) CES1DNMT1ATMMEN1KMT2A
SCHEMBL10000558 0.80 GAA (0.50) CES1ATMMEN1KMT2ACDC25B
SCHEMBL11130086 0.79 BCL2 (0.61) TTRCES1ELANEBCL2MCL1
SCHEMBL10000573 0.78 RAB9A (0.58) ATMMEN1KMT2ARAB9AALDH1A1
SCHEMBL10000566 0.77 KMT2A (0.38) CES1DNMT1ATMMEN1KMT2A
SCHEMBL11040014 0.76 DNMT1 (0.50) TTRCES1DNMT1ELANEATM
SCHEMBL14330793 0.76 TTR (0.46) TTRDNMT1ELANEBCL2MCL1
SCHEMBL9512512 0.76 TTR (0.53) TTRELANEBCL2MCL1MEN1
SCHEMBL8893098 0.73 CYP3A4 (0.59) CES1DNMT1BCL2MCL1RAB9A
SCHEMBL9241029 0.73 ATM (0.57) CES1DNMT1ELANEATMBCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7244548-B2 Photopolymerizing composition and photopolymerizing recording medium manufactured using the same and used to manufacture 3D optical memory having ultra-high information storage capacity SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-07-17 US disclosed