SCHEMBL10000573

SCHEMBL10000573

Cc1c2c(cc3ccccc13)C(=O)c1cc3ccccc3nc1-2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.58
NPC1 O15118 4/20 0.58
ATM Q13315 1/20 0.44
PDE10A Q9Y233 2/20 0.44
MBNL1 Q9NR56 1/20 0.43
TOP2A P11388 4/20 0.40
TOP2B Q02880 4/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
MAPT P10636 3/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MAOB P27338 2/20 0.37
APAF1 O14727 1/20 0.37
TDP2 O95551 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10028054 0.82 RAB9A (0.54) RAB9ANPC1TOP2ATOP2BMAPT
SCHEMBL10000558 0.78 GAA (0.50) ATMTOP2ATDP1MAPTMEN1
SCHEMBL14445486 0.78 TTR (0.45) RAB9ANPC1ATMMAPTMAPK1
SCHEMBL10000578 0.77 CA12 (0.41) RAB9ANPC1ATMMEN1KMT2A
SCHEMBL17207363 0.76 CES1 (0.44) RAB9AATMMAPK1ALDH1A1MEN1
SCHEMBL10000566 0.75 KMT2A (0.38) RAB9AATMMAPTALDH1A1MEN1
SCHEMBL7464992 0.74 RAB9A (1.00) RAB9ANPC1ATMMAPTMAPK1
SCHEMBL7648567 0.74 RAB9A (0.86) RAB9ANPC1ATMMBNL1MAPT
SCHEMBL31538695 0.74 RAB9A (1.00) RAB9ANPC1ATMMAPTMAPK1
SCHEMBL10000572 0.72 MAPT (0.54) RAB9ANPC1PDE10AMBNL1TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2015-11-26 US disclosed
US-9096529-B2 Metal complex compound and organic light emitting diode device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-04 US disclosed
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150340628-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 RAB9A 720/4885NPC1 1702/4885ATM 3185/4885
US-20120012824-A1 METAL COMPLEX COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME AP1M1, MT-CO1, AP2M1 RAB9A 720/4885NPC1 1702/4885ATM 3185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.