Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | BCR | P11274 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677624 | 0.87 | GCGR (0.41) | GCGRKDM4EGAAMAPTMAPK1 | |
| SCHEMBL2425237 | 0.85 | GCGR (0.43) | GCGRKDM4EGAAMAPTMAPK1 | |
| SCHEMBL508428 | 0.84 | MAPT (0.45) | GCGRKDM4EGAAMAPTMAPK1 | |
| SCHEMBL4682811 | 0.83 | TLR8 (0.41) | ALDH1A1KDM2BKDM4CADORA3 | |
| SCHEMBL14445949 | 0.81 | GCGR (0.51) | GCGRMAPT | |
| SCHEMBL4682127 | 0.81 | GCGR (0.53) | GCGRGAAMAPTALDH1A1RECQL | |
| SCHEMBL5549267 | 0.78 | MAPT (0.44) | GCGRKDM4EGAAMAPTMAPK1 | |
| SCHEMBL4685132 | 0.78 | MAPT (0.42) | GCGRKDM4EGAAMAPTMAPK1 | |
| SCHEMBL2424125 | 0.77 | MAPT (0.44) | GCGRKDM4EGAAMAPTMAPK1 | |
| SCHEMBL2424870 | 0.77 | GCGR (0.42) | GCGRKDM4EGAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |