Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ASIC1 | P78348 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | GIPR | P48546 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14290243 | 0.90 | GCGR (0.49) | GCGRMAPTASIC1SMN1; SMN2HDAC1 | |
| SCHEMBL4683641 | 0.89 | NPBWR1 (0.47) | MAPTASIC1SMN1; SMN2HDAC1 | |
| SCHEMBL4682127 | 0.88 | GCGR (0.53) | GCGRMAPTSMN1; SMN2HDAC1GIPR | |
| SCHEMBL13425461 | 0.86 | MEN1 (0.53) | MAPTSMN1; SMN2LMNAHDAC1 | |
| SCHEMBL23297371 | 0.81 | MAPT (0.67) | GCGRMAPTSMN1; SMN2HDAC1 | |
| SCHEMBL14445954 | 0.81 | GCGR (0.42) | GCGRMAPT | |
| SCHEMBL2425237 | 0.81 | GCGR (0.43) | GCGRMAPTHDAC1GIPRCYP3A4 | |
| SCHEMBL508428 | 0.80 | MAPT (0.45) | GCGRMAPT | |
| SCHEMBL14290130 | 0.79 | GCGR (0.50) | GCGRMAPTSMN1; SMN2HDAC1 | |
| SCHEMBL22613652 | 0.78 | MAPT (0.44) | MAPTSMN1; SMN2LMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |