Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.86 |
| ▸ | DRD1 | P21728 | 1/20 | 0.86 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.86 |
| ▸ | PDE4A | P27815 | 1/20 | 0.86 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.37 |
| ▸ | ITGAV | P06756 | 3/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.37 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.37 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NECTIN4 | Q96NY8 | 2/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | SHH | Q15465 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14446808 | 1.00 | CTSL (0.86) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL14446360 | 1.00 | CTSL (0.86) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL14446707 | 0.96 | CTSL (0.79) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL10157516 | 0.95 | CTSL (0.88) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL21250583 | 0.95 | CTSL (0.88) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8422213 | 0.95 | CTSL (0.88) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8420524 | 0.95 | CTSL (0.88) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8227154 | 0.95 | CTSL (0.88) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8415773 | 0.95 | CTSL (0.88) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8221832 | 0.95 | CTSL (0.88) | CTSLDRD1PTGS1PDE4AEPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348382-A1 | LYOPHILIZED INJECTABLE COMPOSITIONS OF DAPTOMYCIN | DR. REDDY'S LABORATORIES LIMITED (IN) | 2017-12-07 | — | — | US | disclosed |
| US-20170216396-A1 | DAPTOMYCIN FORMULATIONS AND USES THEREOF | HOSPIRA AUSTRALIA PTY LTD. (AU) | 2017-08-03 | — | — | US | disclosed |
| US-9655946-B2 | Daptomycin formulations and uses thereof | HOSPIRA AUSTRALIA PTY LTD. (AU) | 2017-05-23 | — | — | US | disclosed |
| US-20150313958-A1 | DAPTOMYCIN FORMULATIONS AND USES THEREOF | HOSPIRA AUSTRALIA PTY LTD. (AU) | 2015-11-05 | — | — | US | disclosed |
| US-8853357-B2 | High purity lipopeptides | CUBIST PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-8431539-B2 | Formulations of daptomycin | EAGLE PHARMACEUTICALS, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-7262268-B2 | Lipopeptide stereoisomers, methods for preparing same, and useful intermediates | CUBIST PHARMACEUTICALS, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-20070191280-A1 | High Purity Lipopeptides | CUBIST PHARMACEUTICALS LLC (CH) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216396-A1 | DAPTOMYCIN FORMULATIONS AND USES THEREOF | NRDC, NACA, IL17A | CTSL 110/4885DRD1 2022/4885PTGS1 2966/4885 |
| US-20170348382-A1 | LYOPHILIZED INJECTABLE COMPOSITIONS OF DAPTOMYCIN | NRDC, PCSK7, PTMS | CTSL 220/4885DRD1 3380/4885PTGS1 3519/4885 |
| US-20150313958-A1 | DAPTOMYCIN FORMULATIONS AND USES THEREOF | NRDC, NACA, IL17A | CTSL 110/4885DRD1 2022/4885PTGS1 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.