Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14706053 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| SCHEMBL14705942 | 0.87 | KMT2A (0.59) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| Hydrochloric Acid SCHEMBL23035272 | 0.87 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| SCHEMBL14705933 | 0.87 | KMT2A (0.59) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| SCHEMBL14448354 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| Hydrochloric Acid SCHEMBL23035188 | 0.86 | KMT2A (0.58) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| Hydrochloric Acid SCHEMBL23035203 | 0.86 | KMT2A (0.58) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| SCHEMBL23047462 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| SCHEMBL8392311 | 0.83 | KMT2A (0.64) | ALDH1A1KMT2AMEN1RECQLNPSR1 | |
| SCHEMBL8394335 | 0.81 | SMN1; SMN2 (0.56) | ALDH1A1KMT2AMEN1RECQLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203140-A1 | N-hydroxyguanidines as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION | 2007-08-30 | — | — | US | disclosed |
| WO-2007095050-A2 | N-HYDROXYGUANIDINES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | INCYTE CORPORATION (US) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203140-A1 | N-hydroxyguanidines as modulators of indoleamine 2,3-dioxygenase | IDO1, IDO2, HNMT | ALDH1A1 764/4885KMT2A 882/4885MEN1 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.