Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CPN1 | P15169 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178373 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2GAAPOLBCPN1CPB2 | |
| SCHEMBL14344751 | 0.82 | CPN1 (0.41) | SMN1; SMN2GAAPOLBCPN1CPB2 | |
| SCHEMBL12132347 | 0.76 | MAPT (0.66) | SMN1; SMN2GAAPOLBMAPTTSHR | |
| SCHEMBL14344917 | 0.76 | MAPT (0.44) | SMN1; SMN2GAAPOLBCPN1CPB2 | |
| SCHEMBL8277480 | 0.76 | GAA (0.55) | SMN1; SMN2GAAPOLBCPN1CPB2 | |
| SCHEMBL14621736 | 0.75 | CPN1 (0.47) | SMN1; SMN2GAACPN1CPB2MAPT | |
| SCHEMBL8279747 | 0.74 | LMNA (0.52) | SMN1; SMN2GAAPOLBCPN1CPB2 | |
| SCHEMBL27416738 | 0.71 | SMN1; SMN2 (0.45) | SMN1; SMN2GAAPOLBMAPTTSHR | |
| SCHEMBL10143821 | 0.69 | CPN1 (0.46) | SMN1; SMN2GAACPN1CPB2MAPT | |
| SCHEMBL14366136 | 0.69 | CPN1 (0.42) | SMN1; SMN2GAACPN1CPB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373194-B1 | BENZAMIDE INHIBITORS OF FACTOR Xa | MILLENNIUM PHARM INC (US) | 2007-08-01 | — | — | EP | disclosed |