Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178373 | 0.83 | SMN1; SMN2 (0.59) | CPN1CPB2SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL14448387 | 0.82 | SMN1; SMN2 (0.42) | CPN1CPB2SMN1; SMN2MAPTGAA | |
| SCHEMBL14344917 | 0.79 | MAPT (0.44) | CPN1CPB2SMN1; SMN2MAPTGAA | |
| SCHEMBL14448370 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTGAAALDH1A1POLB | |
| SCHEMBL12132347 | 0.79 | MAPT (0.66) | SMN1; SMN2MAPTGAAALDH1A1POLB | |
| SCHEMBL8277480 | 0.79 | GAA (0.55) | CPN1CPB2SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL28807501 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTGAAALDH1A1POLB | |
| SCHEMBL14621736 | 0.78 | CPN1 (0.47) | CPN1CPB2SMN1; SMN2MAPTGAA | |
| SCHEMBL13270668 | 0.76 | TP53 (0.40) | SMN1; SMN2MAPTGAAALDH1A1POLB | |
| SCHEMBL8279747 | 0.76 | LMNA (0.52) | CPN1CPB2SMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1373194-B1 | BENZAMIDE INHIBITORS OF FACTOR Xa | MILLENNIUM PHARM INC (US) | 2007-08-01 | — | — | EP | disclosed |