Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138566 | 0.87 | IGF1R (0.50) | ALDH1A1LMNAIGF1RHPGDMAPK1 | |
| SCHEMBL14449395 | 0.86 | ALDH1A1 (0.50) | ALDH1A1LMNAIGF1RHPGDMAPK1 | |
| SCHEMBL30166910 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAIGF1RHPGDMAPK1 | |
| SCHEMBL13983006 | 0.80 | ALDH1A1 (0.63) | ALDH1A1LMNAIGF1RHPGDMAPK1 | |
| SCHEMBL7678691 | 0.78 | GRM6 (0.40) | ALDH1A1LMNAHPGDMAPK1KMT2A | |
| SCHEMBL140029 | 0.76 | IGF1R (0.50) | ALDH1A1LMNAIGF1RHPGDMAPK1 | |
| SCHEMBL14142059 | 0.75 | LMNA (0.51) | ALDH1A1LMNAIGF1RMAPK1KMT2A | |
| SCHEMBL3141664 | 0.74 | IGF1R (0.48) | ALDH1A1LMNAIGF1RHPGDMAPK1 | |
| SCHEMBL13830529 | 0.73 | IGF1R (0.43) | LMNAIGF1RHPGDKMT2A | |
| SCHEMBL29951621 | 0.73 | NPSR1 (0.61) | ALDH1A1LMNAMAPK1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007085188-A1 | PYRROLO [3,2-C] PYRIDINE-4-ONE 2-INDOLINONE PROTEIN KINASE INHIBITORS | SHANGHAI HENGRUI PHARMACEUTICAL CO. LTD. (CN) | 2007-08-02 | — | — | WO | disclosed |