SCHEMBL14449643

SCHEMBL14449643

CCCCCCCc1cc(F)c2c(c1)CCC(c1cc(F)c(F)c(F)c1)O2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 12/20 0.35
CNR1 P21554 10/20 0.35
PTGS2 P35354 3/20 0.33
OPRM1 P35372 3/20 0.33
TRPV1 Q8NER1 2/20 0.33
NR1I2 O75469 2/20 0.33
LDHA P00338 2/20 0.33
TRPM8 Q7Z2W7 2/20 0.33
GPR55 Q9Y2T6 2/20 0.33
ACE2 Q9BYF1 1/20 0.33
MLNR O43193 1/20 0.33
PDE9A O76083 1/20 0.33
ABCB11 O95342 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
HTR1A P08908 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4638432 0.83 ESR1 (0.40) CNR2CNR1DRD2SLC6A2HTR2A
SCHEMBL14449689 0.80 RARB (0.36) CNR2CNR1CSF1R
SCHEMBL14449667 0.78 ESR1 (0.35) CNR2CNR1PTGS2OPRM1TRPV1
SCHEMBL5482894 0.77 GPR119 (0.32) CSF1R
SCHEMBL14449819 0.77 PTGS2 (0.33) PTGS2CYP3A4DRD2SLC6A2HTR2A
SCHEMBL14071434 0.76 CSF1R (0.33) CSF1R
SCHEMBL14071282 0.76 CSF1R (0.34) CYP3A4CYP2D6CYP2C9CYP2C19CSF1R
SCHEMBL14449663 0.74 CSF1R (0.31) CSF1R
SCHEMBL14449650 0.74 CSF1R (0.36) DRD2HTR2CHTR2BCSF1RDRD3
SCHEMBL14449645 0.74 CSF1R (0.38) DRD2CSF1RDRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247355-B2 Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition CHISSO CORPORATION (JP) 2007-07-24 US disclosed