Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11926955 | 0.86 | HTR1A (0.38) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL14449366 | 0.84 | HTR2B (0.37) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL5985680 | 0.80 | HTR2B (0.39) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL12301085 | 0.78 | KDM4E (0.36) | HTR2CMMP12ALDH1A1GAAMAPT | |
| SCHEMBL12233255 | 0.73 | KDM4E (0.35) | HTR2CMMP12ALDH1A1GAAKDM4E | |
| SCHEMBL20994730 | 0.72 | ADRA2A (0.40) | ALDH1A1GAAMAPTKDM4EHTR5A | |
| SCHEMBL16142345 | 0.71 | — | — | |
| SCHEMBL14449365 | 0.70 | HTR2B (0.37) | HTR1ASLC6A2HTR2CHTR2BSIGMAR1 | |
| SCHEMBL14449367 | 0.70 | KDM4E (0.33) | HTR2CMMP12ALDH1A1GAAMAPT | |
| SCHEMBL8533498 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247355-B2 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |
| US-7247355-B2 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |