Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 17/20 | 0.50 |
| ▸ | CCR6 | P51684 | 3/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13479527 | 0.88 | CXCR2 (0.52) | CXCR2CCR6CXCR1 | |
| SCHEMBL14450207 | 0.86 | CXCR2 (0.50) | CXCR2CCR6CXCR1 | |
| SCHEMBL12262455 | 0.81 | CXCR2 (0.74) | CXCR2CCR6CXCR1 | |
| SCHEMBL12569949 | 0.81 | CXCR2 (0.74) | CXCR2CCR6CXCR1 | |
| SCHEMBL12087272 | 0.81 | CXCR2 (0.74) | CXCR2CCR6CXCR1 | |
| SCHEMBL12262461 | 0.81 | CXCR2 (0.74) | CXCR2CCR6CXCR1 | |
| SCHEMBL12263173 | 0.79 | CXCR2 (0.70) | CXCR2CCR6CXCR1 | |
| SCHEMBL12087142 | 0.78 | CCR6 (0.57) | CXCR2CCR6CXCR1 | |
| SCHEMBL13479605 | 0.76 | CXCR2 (0.55) | CXCR2CCR6CXCR1 | |
| SCHEMBL13479627 | 0.74 | CXCR2 (0.52) | CXCR2CCR6CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1818325-A2 | 3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2007-08-15 | — | — | EP | disclosed |