Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 11/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 9/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12087222 | 0.80 | CCR6 (0.85) | CCR6CXCR2CXCR1 | |
| SCHEMBL14450107 | 0.78 | CXCR2 (0.50) | CCR6CXCR2CXCR1 | |
| SCHEMBL12086660 | 0.77 | CCR6 (0.80) | CCR6CXCR2CXCR1 | |
| SCHEMBL20732822 | 0.72 | CCR6 (1.00) | CCR6CXCR2CXCR1 | |
| SCHEMBL13479554 | 0.71 | CXCR2 (0.69) | CCR6CXCR2CXCR1 | |
| SCHEMBL14511299 | 0.70 | CXCR2 (0.54) | CXCR2CXCR1 | |
| SCHEMBL13479605 | 0.69 | CXCR2 (0.55) | CCR6CXCR2CXCR1 | |
| SCHEMBL20721288 | 0.69 | CCR6 (0.66) | CCR6CXCR2CXCR1 | |
| SCHEMBL14450159 | 0.69 | CCR6 (0.69) | CCR6CXCR2CXCR1 | |
| SCHEMBL12087261 | 0.68 | CXCR2 (1.00) | CCR6CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539678-B1 | 3,4-DI-SUBSTITUTED CYCLOBUTENE-1, 2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS | MERCK SHARP & DOHME (US) | 2012-09-05 | — | — | EP | disclosed |