Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 7/20 | 0.69 |
| ▸ | CXCR2 | P25025 | 13/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14450153 | 0.83 | CCR6 (0.61) | CCR6CXCR2CXCR1 | |
| SCHEMBL12260594 | 0.82 | CCR6 (1.00) | CCR6CXCR2CXCR1 | |
| SCHEMBL12260593 | 0.81 | CCR6 (0.98) | CCR6CXCR2CXCR1 | |
| SCHEMBL246834 | 0.78 | CCR6 (0.92) | CCR6CXCR2CXCR1 | |
| SCHEMBL13479554 | 0.76 | CXCR2 (0.69) | CCR6CXCR2CXCR1 | |
| SCHEMBL14450207 | 0.76 | CXCR2 (0.50) | CCR6CXCR2CXCR1 | |
| SCHEMBL13479527 | 0.76 | CXCR2 (0.52) | CCR6CXCR2CXCR1 | |
| SCHEMBL14450802 | 0.74 | CXCR2 (0.53) | CCR6CXCR2CXCR1 | |
| SCHEMBL14511371 | 0.74 | CXCR2 (0.64) | CCR6CXCR2CXCR1 | |
| SCHEMBL13479605 | 0.74 | CXCR2 (0.55) | CCR6CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1818325-A2 | 3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2007-08-15 | — | — | EP | disclosed |