Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | TYMS | P04818 | 1/20 | 0.60 |
| ▸ | POLA1 | P09884 | 1/20 | 0.57 |
| ▸ | POLD1 | P28340 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21068055 | 0.91 | TK1 (0.74) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL7038209 | 0.91 | TK1 (0.74) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL288740 | 0.91 | TK1 (0.74) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL9600789 | 0.90 | POLB (0.71) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL26479960 | 0.89 | TK1 (0.71) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL17577466 | 0.89 | TK1 (0.71) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL2053943 | 0.88 | TK1 (0.70) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL30583236 | 0.87 | TK1 (0.77) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL4747720 | 0.87 | TK1 (0.77) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL15989038 | 0.87 | TK1 (0.71) | TK1POLBTYMSPOLA1POLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011036505-A1 | NEW 6-SUBSTITUTED PYRIMIDINE DERIVATIVES | Sveučilište u Zagrebu (HR) | 2011-03-31 | — | — | WO | disclosed |