SCHEMBL144503

SCHEMBL144503

O=S(=O)(O)c1ccc(/N=N/c2c(O)ccc3ccccc23)cc1.[NaH]

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.78
KMT2A Q03164 5/20 0.78
MEN1 O00255 4/20 0.78
TDP1 Q9NUW8 4/20 0.72
MAPK1 P28482 3/20 0.72
GAA P10253 2/20 0.72
L3MBTL1 Q9Y468 2/20 0.67
LMNA P02545 1/20 0.67
ALPL P05186 1/20 0.67
HSP90AA1 P07900 1/20 0.67
ALPI P09923 1/20 0.67
ALPG P10696 1/20 0.67
CASP3 P42574 1/20 0.67
RECQL P46063 1/20 0.67
MMP14 P50281 1/20 0.67
SENP8 Q96LD8 1/20 0.67
SENP7 Q9BQF6 1/20 0.67
SENP6 Q9GZR1 1/20 0.67
THRB P10828 4/20 0.66
CYP1A2 P05177 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL144505 1.00 MAPT (0.78) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL4412992 0.99 MAPT (0.80) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL11336943 0.99 MAPT (0.80) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL29376978 0.99 MAPT (0.80) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL109165 0.99 MAPT (0.80) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL92162 0.99 MAPT (0.80) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL30842302 0.97 MAPT (0.78) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL19000765 0.88 MAPT (0.79) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL11877643 0.87 MAPT (0.66) MAPTKMT2AMEN1TDP1MAPK1
SCHEMBL11877650 0.87 MAPT (0.66) MAPTKMT2AMEN1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2930126-B1 Fashionable aerosol dye HENKEL AG & CO KGAA (DE) 2019-10-09 EP claimed
US-7294370-B2 Polarizing and optical compensating films for visible, ultraviolet and infrared parts of the electromagnetic spectrum KENT STATE UNIVERSITY (US) 2007-11-13 US claimed
EP-3229918-B1 COMPOSITION AND PROCEDURE FOR TREATING KERATINIC FIBERS WITH FLASH EVAPORATION HENKEL AG & CO KGAA (DE) 2024-03-13 EP disclosed
US-20220145038-A1 FUNCTONALIZED CELLULAR ELASTOMER FOAM, AND A USE OF A CELLULAR ELASTOMER FOAM AS A CATALYST SUBSTRATE-- CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-05-12 US disclosed
US-11267947-B2 Method for modifying the surface properties of elastomer cellular foams UNIVERSITE DE STRASBOURG (FR) 2022-03-08 US disclosed
US-10179093-B2 Compositions and methods for coloring keratinic fibers HENKEL AG & CO. KGAA (DE) 2019-01-15 US disclosed
US-10111508-B2 Composition and method for treating keratin fibers with flash evaporation HENKEL AG & CO. KGAA (DE) 2018-10-30 US disclosed
US-20170312188-A1 COMPOSITIONS AND METHODS FOR COLORING KERATINIC FIBERS HENKEL AG & CO. KGAA (DE) 2017-11-02 US disclosed
US-20170273424-A1 COMPOSITION AND METHOD FOR TREATING KERATIN FIBERS WITH FLASH EVAPORATION HENKEL AG & CO. KGAA (DE) 2017-09-28 US disclosed
US-20170210872-A1 METHOD FOR MODIFYING THE SURFACE PROPERTIES OF ELASTOMER CELLULAR FOAMS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-07-27 US disclosed
US-9693937-B2 Foil applicator HENKEL AG & CO. KGAA (DE) 2017-07-04 US disclosed
US-6558433-B2 Oxidation hair dye WELLA AG (DE) 2003-05-06 US disclosed
US-20030041392-A1 Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same Wella GmbH (DE) 2003-03-06 US disclosed
US-6485529-B1 Agent and method for coloring fibers WELLA AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed
US-6461390-B1 Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same WELLA AKTIENGESELLSCHAFT (DE) 2002-10-08 US disclosed
US-6361571-B1 USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES WELLA AKTIENGESELLSCHAFT (DE) 2002-03-26 US disclosed
US-4784959-A Method of detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1988-11-15 US disclosed
US-4756854-A Method and apparatus for detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1988-07-12 US disclosed
US-4745797-A Method and apparatus for detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1988-05-24 US disclosed
US-4615828-A Method and apparatus for detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1986-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030041392-A1 Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same KRT18, SCNN1B, DDAH1 MAPT 2639/4885KMT2A 225/4885MEN1 1222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.