SCHEMBL1445052

SCHEMBL1445052

Clc1ccc2[nH]cnc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
PARP1 P09874 1/20 0.52
MAPT P10636 3/20 0.50
F7 P08709 2/20 0.47
F3 P13726 2/20 0.47
KDM4E B2RXH2 2/20 0.47
AHR P35869 2/20 0.47
LTA4H P09960 1/20 0.47
NR4A2 P43354 1/20 0.47
APEX1 P27695 1/20 0.47
RECQL P46063 1/20 0.47
BLM P54132 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
RXFP1 Q9HBX9 1/20 0.45
DPP4 P27487 1/20 0.44
DPP8 Q6V1X1 1/20 0.44
PRKCI P41743 1/20 0.44
DYRK1A Q13627 1/20 0.43
RAD52 P43351 1/20 0.42
CMA1 P23946 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29908920 1.00 ALDH1A1 (0.56) ALDH1A1PARP1MAPTF7F3
SCHEMBL11404855 0.98 ALDH1A1 (0.55) ALDH1A1PARP1MAPTF7F3
SCHEMBL8817622 0.92 PRKCI (0.52) ALDH1A1PARP1MAPTKDM4EAPEX1
Imidazole SCHEMBL3397303 0.86 ALDH1A1 (0.45) ALDH1A1PARP1MAPTF7F3
SCHEMBL13373351 0.84 ALDH1A1 (0.46) ALDH1A1PARP1MAPTKDM4EAPEX1
SCHEMBL30544126 0.83 PRKCI (0.59) ALDH1A1PARP1MAPTKDM4EPRKCI
SCHEMBL1445055 0.83 PRKCI (0.59) ALDH1A1PARP1MAPTKDM4EPRKCI
Butylamine SCHEMBL8655792 0.82 DPP4 (0.43) ALDH1A1PARP1MAPTKDM4EAPEX1
SCHEMBL28178017 0.81 DPP4 (0.51) ALDH1A1PARP1MAPTAHRDPP4
SCHEMBL11404862 0.81 PRKCI (0.57) ALDH1A1PARP1MAPTKDM4EPRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037720-A MOF glass/epoxy resin anti-corrosion composite coating and preparation method thereof 华北水利水电大学 2026-05-15 CN claimed
CN-122013163-A Uniform compact bright compound additive for electroless copper plating and preparation method thereof 杭州金昇粉体新材料有限公司 2026-05-12 CN claimed
EP-4089823-B1 SEPARATOR, ELECTRICAL APPARATUS CONTAINING SUCH SEPARATOR, AND PREPARATION METHOD THEREOF CONTEMPORARY AMPEREX TECHNOLOGY HONG KONG LTD (HK) 2026-04-01 EP claimed
US-12469929-B2 Separator, electrical apparatus containing such separator, and preparation method thereof CONTEMPORARY AMPEREX TECHNOLOGY (HONG KONG) LIMITED (CN) 2025-11-11 US claimed
EP-4635592-A1 COLLOIDAL FLOATING MEMBRANE AND PREPARATION METHOD THEREOF Consejo Superior De Investigaciones Científicas - CSIC (ES) 2025-10-22 EP claimed
CN-116262207-B Method for electrochemically synthesizing metal-organic framework membrane and application of metal-organic framework membrane in gas separation 中国科学院大连化学物理研究所 2025-05-16 CN claimed
CN-119824424-A WO (WO) for photocathode protection3-ZIFs composite membrane and application thereof 河南省科学院 2025-04-15 CN claimed
CN-119793232-A MOF crystal-glass composite membrane for gas separation and preparation method and application thereof 衢州膜材料创新研究院 2025-04-11 CN claimed
US-12246291-B2 Metal organic framework glass membrane and preparation method thereof NINGBO UNIVERSITY (CN) 2025-03-11 US claimed
US-12230836-B2 Organic-inorganic hybrid complex and coating composition comprising same, separator, secondary battery, battery module, battery pack and power consuming device CONTEMPORARY AMPEREX TECHNOLOGY (HONG KONG) LIMITED (CN) 2025-02-18 US claimed
CN-103224535-A Metal or ligand replacement method for construction of mixed metal or mixed ligand zeolitic imidazolate frameworks (ZIFs) DALIAN CHEMICAL PHYSICS INST 2013-07-31 CN claimed
CN-102335626-B Method for synthesizing micro/nano zeolitic imidazolate frameworks (ZIFs) CHINESE ACAD INST CHEMISTRY 2013-01-09 CN claimed
CN-101912737-B Method for preparing metal organic framework supported film NANJING UNIVERSITY OF TECHNOLOGY 2012-12-19 CN claimed
CN-102731538-A Preparation method of nanometer-to-micrometer scale zeolitic imidazolate frameworks (ZIFs) UNIV CHINA PETROLEUM 2012-10-17 CN claimed
CN-102335626-A Method for synthesizing micro/nano zeolitic imidazolate frameworks (ZIFs) CHINESE ACAD INST CHEMISTRY 2012-02-01 CN claimed
WO-2011033235-A1 COMPOSITE MATERIAL COMPRISING AN ORGANIC-INORGANIC MATERIAL, PREPARATION PROCESS, AND USES TREDI (FR) 2011-03-24 WO claimed
CN-101912737-A Method for preparing metal organic framework supported film NANJING UNIVERSITY OF TECHNOLOGY 2010-12-15 CN claimed
CN-1955178-A New benzimidazole derivative BANYU PHARMA CO LTD (JP) 2007-05-02 CN claimed
CN-1668615-A Novel benzimidazole derivatives BANYU PHARMA CO LTD (JP) 2005-09-14 CN claimed
US-4329459-A ENDOPEROXIDE CYCLOXGENASE INHIBITORS THE UPJOHN COMPANY (US) 1982-05-11 US claimed