Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 3/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MARS1 | P56192 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17137631 | 0.83 | MAPT (0.49) | DPP4DPP8MAPTALDH1A1PARP1 | |
| SCHEMBL4976085 | 0.83 | DPP4 (0.40) | DPP4DPP8MAPTALDH1A1PARP1 | |
| SCHEMBL30026126 | 0.83 | QPCTL (0.51) | MAPTQPCTQPCTLLMNA | |
| SCHEMBL14919896 | 0.82 | IDO1 (0.51) | DPP4DPP8MAPTALDH1A1PARP1 | |
| SCHEMBL13373351 | 0.82 | ALDH1A1 (0.46) | MAPTALDH1A1PARP1QPCTQPCTL | |
| SCHEMBL1445052 | 0.81 | ALDH1A1 (0.56) | DPP4DPP8AHRMAPTALDH1A1 | |
| SCHEMBL29908920 | 0.81 | ALDH1A1 (0.56) | DPP4DPP8AHRMAPTALDH1A1 | |
| SCHEMBL11404855 | 0.79 | ALDH1A1 (0.55) | DPP4DPP8AHRMAPTALDH1A1 | |
| SCHEMBL31143361 | 0.77 | MAPT (0.50) | MAPTALDH1A1QPCTQPCTLSMN1; SMN2 | |
| SCHEMBL6008269 | 0.77 | MAPT (0.50) | MAPTALDH1A1QPCTQPCTLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107312008-B | A kind of catalysis prepares the catalyst and system and method for benzimidazole simultaneously [2,1-b] quinoline -6- ketone derivatives | 马鞍山市泰博化工科技有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-107312008-A | A kind of easy catalysis prepares the catalyst and system and method for benzimidazole simultaneously ketone derivatives of [2,1 b] quinoline 6 | 马鞍山市泰博化工科技有限公司 | 2017-11-03 | — | — | CN | disclosed |