Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412085 | 0.89 | ALDH1A1 (0.43) | TSHRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2409605 | 0.79 | MEN1 (0.57) | TSHRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2412445 | 0.77 | SMN1; SMN2 (0.48) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL5561572 | 0.76 | MAPT (0.54) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL2408480 | 0.76 | MAPT (0.43) | KMT2AMEN1LMNAMAPTPOLB | |
| SCHEMBL2415348 | 0.75 | HSD17B10 (0.49) | ALDH1A1LMNAMAPTRAB9AGAA | |
| SCHEMBL2412833 | 0.74 | MAPT (0.46) | TSHRKMT2AMEN1LMNAMAPT | |
| SCHEMBL2413792 | 0.74 | CTPS1 (0.48) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL2413442 | 0.74 | CTPS1 (0.48) | TSHRKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2412613 | 0.73 | MAPT (0.35) | TSHRKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1816128-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2007-08-08 | — | — | EP | disclosed |