Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409605 | 0.86 | MEN1 (0.57) | MAPTALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL2412445 | 0.79 | SMN1; SMN2 (0.48) | MAPTALDH1A1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL2415348 | 0.77 | HSD17B10 (0.49) | MAPTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL2413792 | 0.77 | CTPS1 (0.48) | MAPTALDH1A1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL2413442 | 0.77 | CTPS1 (0.48) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14451659 | 0.76 | TSHR (0.46) | MAPTALDH1A1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL2415598 | 0.76 | POLB (0.51) | MAPTALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL12274759 | 0.75 | MEN1 (0.52) | MAPTALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL2416071 | 0.75 | LMNA (0.60) | MAPTSMN1; SMN2KMT2AL3MBTL1MEN1 | |
| SCHEMBL2418139 | 0.74 | POLQ (0.41) | MAPTALDH1A1HPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1816128-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2007-08-08 | — | — | EP | disclosed |