Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 17/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 8/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2210287 | 0.99 | ALDH1A1 (0.41) | ALDH1A1GAAPTGER4PTGER3PTGER2 | |
| SCHEMBL2211707 | 0.83 | ALDH1A1 (0.39) | ALDH1A1GAALMNA | |
| SCHEMBL12432872 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GAAPTGER4PTGER3PTGER2 | |
| SCHEMBL5819682 | 0.81 | PTGER4 (0.36) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2213020 | 0.81 | GAA (0.47) | ALDH1A1GAAPTGER4PTGER3PTGER2 | |
| SCHEMBL14470831 | 0.80 | — | — | |
| SCHEMBL6686327 | 0.80 | PTGER4 (0.41) | ALDH1A1PTGER4PTGER3PTGER2 | |
| SCHEMBL6686330 | 0.80 | PTGER4 (0.41) | ALDH1A1PTGER4PTGER3PTGER2 | |
| SCHEMBL12288856 | 0.76 | ALDH1A1 (0.47) | ALDH1A1GAAPTGER4PTGER3PTGER2 | |
| SCHEMBL24795959 | 0.74 | PDK2 (0.41) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238710-B2 | EP4 receptor agonist, compositions and methods thereof | MERCK FROSST CANADA, LTD. (CA) | 2007-07-03 | — | — | US | disclosed |