Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 16/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 8/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2210287 | 0.82 | ALDH1A1 (0.41) | PTGER4PTGER3PTGER2 | |
| SCHEMBL14453240 | 0.81 | ALDH1A1 (0.39) | PTGER4PTGER3PTGER2 | |
| SCHEMBL3675530 | 0.75 | PTGER4 (0.35) | PTGER4PTGER3PTGER2 | |
| SCHEMBL1401084 | 0.75 | PDK2 (0.41) | PTGER4PTGER3PTGER2 | |
| SCHEMBL24795959 | 0.75 | PDK2 (0.41) | PTGER4PTGER3PTGER2 | |
| SCHEMBL3679333 | 0.74 | PDK2 (0.34) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6686327 | 0.72 | PTGER4 (0.41) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6686330 | 0.72 | PTGER4 (0.41) | PTGER4PTGER3PTGER2 | |
| SCHEMBL21389332 | 0.70 | DUT (0.33) | — | |
| SCHEMBL24795965 | 0.70 | DUT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613621-A1 | PROSTAGLANDIN ANALOGS AS EP4 RECEPTOR AGONISTS | Merck Frosst Canada Ltd. (CA) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004085430-A1 | PROSTAGLANDIN ANALOGS AS EP4 RECEPTOR AGONISTS | MERCK FROSST CANADA LTD. (CA) | 2004-10-07 | — | — | WO | disclosed |