Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 4/20 | 1.00 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.60 |
| ▸ | TUBB | P07437 | 2/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | KRAS | P01116 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576298 | 0.88 | TNFRSF1A (1.00) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14454077 | 0.88 | TNFRSF1A (1.00) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5960638 | 0.83 | TNFRSF1A (1.00) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5960636 | 0.83 | TNFRSF1A (1.00) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7730270 | 0.81 | KDM4E (0.79) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28914840 | 0.81 | GAA (0.79) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1134588 | 0.81 | KDM4E (0.79) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30122806 | 0.81 | GAA (0.79) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29011895 | 0.81 | TNFRSF1A (0.67) | TNFRSF1AABCG2CA1CA2KRAS | |
| SCHEMBL997003 | 0.80 | TUBB4A (0.68) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247714-B2 | Protection against oxidative stress and inflammation by a cytoprotective response element | ATHEROGENICS, INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-7247714-B2 | Protection against oxidative stress and inflammation by a cytoprotective response element | ATHEROGENICS, INC. (US) | 2007-07-24 | — | — | US | disclosed |