Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12161038 | 0.83 | BCHE (0.36) | HSD11B1ALDH1A1HRH3BCHEMAOB | |
| SCHEMBL27397028 | 0.80 | HSD11B1 (0.45) | HSD11B1TP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL16938386 | 0.80 | HSD11B1 (0.61) | HSD11B1ALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL12092350 | 0.80 | HSD11B1 (0.45) | HSD11B1TP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL27482144 | 0.78 | BLM (0.42) | HSD11B1ALDH1A1MEN1KMT2ABCHE | |
| SCHEMBL27395987 | 0.77 | ALDH1A1 (0.48) | HSD11B1ALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL23471258 | 0.75 | TDP1 (0.45) | HSD11B1TP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL13439304 | 0.75 | KMT2A (0.45) | HSD11B1ALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL21015364 | 0.75 | PIK3CD (0.56) | HSD11B1ALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL19169730 | 0.75 | ATM (0.52) | HSD11B1TP53ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007085930-A1 | CYTOTOXIC AGENTS COMPRISING NEW TOMAYMYCIN DERIVATIVES AND THEIR THERAPEUTIC USE | SANOFI-AVENTIS (FR) | 2007-08-02 | — | — | WO | disclosed |